New York Giants vs San Francisco 49ers 9/21/2023 Week 3 NFL Betting Picks, Odds and Analysis

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New York Giants vs San Francisco 49ers 9/21/2023 – On Thursday, the New York Giants are gearing up to face the San Francisco 49ers at Levi’s Stadium at 8:15 PM ET for an electrifying battle under primetime lights. Football fans should prepare themselves for a thrilling experience on display here. Information on NFL Week 3 best betting sites is updated online, offering bettors opportunities to place wagers on their favorite teams.

Amazon Prime makes watching the game an accessible option for fans across the nation, while NFL Game Pass gives online viewers an alternative viewing option. Furthermore, fans can check out ESPN’s dedicated game page for in-depth previews and details regarding this matchup.

Giants vs 49ers 9/24/2023 Game Info

When: Thursday, September 21, 2023
Time: 8:15 PM ET
Where: Levi’s Stadium

New York Giants vs San Francisco 49ers 9/21/2023: Brian Daboll vs Kyle Shanahan

At face value, the New York Giants enter this game as underdogs with an odds spread of +9.5 (-112) while San Francisco 49ers enter as favorites with an odds spread of -10.5. The over/under score for the game has been set at 43.5 points with slightly favoring odds at -111 to offer insight into current betting trends as well as reflect recent performances by both teams.

The Giants have proven their abilities against the spread (ATS) over their last 18 games, posting an impressive 12-6 record against San Francisco 49ers opponents in those matchups. Unfortunately, against other opponents their ATS record has suffered; with just four victories recorded out of five meetings. On the road, the Giants have proven their dependability ATS with an 8-3 record in their last 11 away games and an outstanding 5-2 ATS record against the 49ers during that span. The Giants have experienced difficulties against NFC conference opponents in recent games, posting an overall 3-8-1 straight-up (SU) record over their last 12 matches. Within the NFC West division, they’ve found it even tougher – posting just 3 wins against just 3 losses since 2013. September games often feature low-scoring affairs with 8 of 12 going under in terms of total points scored by either team involved.

Daniel Jones, Saquon Barkley, and Isaiah Hodgins in Focus for the New York Giants

Daniel Jones (QB): Since joining the Giants earlier this season, Daniel Jones has played one game and completed 15 out of 28 passes at 53.6% completion rate. In total he threw for 104 yards with 3.7 average yards per attempt with no touchdowns and two interceptions thrown his way – facing 7 sacks to earn himself a passer rating of 32.4 rating – his performance will be integral in their offensive strategy.

Saquon Barkley (RB): Barkley has made an immediate impactful contribution to his team, amassing 51 rushing yards from 12 attempts – an average of 4.3 yards per carry! While he still needs to score his first touchdown, Barkley’s ability to gain crucial yards will prove indispensable to the New York Giants’ success.

Isaiah Hodgins (WR): Hodgins has quickly established himself as an emerging force in the Giants’ passing game. In one game alone, he recorded one catch out of three targets for 24 yards at an impressive average of 24 yards per catch – his role is expected to expand throughout this season as his touchdown total increases.

NFL Betting Pick San Francisco 49ers -10

San Francisco 49ers fans can get excited for this week’s matchup as their team prepares to take the field, with impressive statistics and star players.

San Francisco 49ers: Winning Team The 49ers have proven their dominance ATS over recent games, posting an impressive 10-3 mark against the spread in their last 13 contests. Their success also extends to their straight-up (SU) record; where they boasted 14-1 play this past season! When facing off with the New York Giants head-on, their fans have typically enjoyed high-scoring affairs with four out of five total games (total going over four times out).

At home, the 49ers have proven an underdog powerhouse – boasting an undefeated 7-0 ATS record over their last seven games against opponents other than the Giants. When facing Giants opponents at home though, their performance drops slightly with just 2-5 in their last seven meetings against ATS performance.

New York Giants Betting Trends

NY Giants are 12-6 ATS in their last 18 games.

NY Giants are 1-4 ATS in their last 5 games against San Francisco.

Giants are 8-3 ATS in their last 11 games on the road.

NY Giants are 5-2 ATS in their last 7 games when playing on the road against San Francisco.

NY Giants are 3-8-1 SU in their last 12 games against an opponent in the National Football Conference.

Giants are 3-10 SU in their last 13 games against an opponent in the National Football Conference West division.

San Francisco 49ers Betting Trends

San Francisco is 10-3 ATS in their last 13 games.

49ers is 14-1 SU in their last 15 games.

The total has gone OVER in 4 of San Francisco’s last 5 games against NY Giants.

San Francisco is 7-0 ATS in their last 7 games at home.

San Francisco is 2-5 ATS in their last 7 games when playing at home against NY Giants.

49ers is 10-1 SU in their last 11 games against an opponent in the National Football Conference.

New York Giants vs San Francisco 49ers

Brock Purdy has played in one game this season and achieved an astounding completion rate of 65.5% by completing 19 of 29 passes with an average of 7.6 yards per attempt and two touchdowns against zero interceptions. Moreover, the 49ers have shown their dominance against NFC conference opponents with an outstanding 10-1 straight-up record against them over their last 11 games, demonstrating their ability to perform consistently against teams within their conference. You can find the latest odds and place your bets on the 49ers at a USA sportsbooks.

Score Prediction: 49ers 34, Giants 31.         

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