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NFL gambling sites favor the home team when the Philadelphia Eagles and San Francisco 49ers clash on Sunday in week 4 NFL action at Levi’s Stadium.

Philadelphia Eagles vs. San Francisco 49ers Odds

Team SP/RL TOTAL ML
Eagles +7 (-105) 46 (-110) +274
49ers -7 (-115) 46 (-110) -340
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Betting Philadelphia Eagles

Philly is the road dog according to the best online sportsbooks. The Philadelphia Eagles need a win to avoid a winless record through the first four weeks. The Philadelphia Eagles have split their last eight games on the road.

Carson Wentz is completing 59.8% of his passes for 737 yards, three TDs and six picks. Wentz has two or more TD passes in four of his last eight games. Dallas Goedert and Zach Ertz have 268 receiving yards and two TDs. DeSean Jackson has 10 grabs.

The Philadelphia Eagles average 117.7 rushing yards per game. Miles Sanders has 190 yards and one touchdown. Philadelphia allows 29 points and 330.7 yards per game. Nathan Gerry has 25 tackles. Brandon Graham has three sacks. Rodney McLeod has two pass deflections.

NFL gambling sites record that Philadelphia is 1-4 ATS in their last five games. 7-1 ATS in their last eight games against San Francisco. And 6-2 SU in their last eight games against San Francisco. The total has gone over in five of Philadelphia’s last five games on the road. Philadelphia is 5-0 ATS in their last five games on the road against San Francisco.

The total has gone over in four of Philadelphia’s last six games against an opponent in the National Football Conference. Philadelphia is 6-13 SU in their last 19 games against an opponent in the National Football Conference West division. And 9-4 ATS in their last 13 games in October.

Betting San Francisco 49ers

The Niners are the home chalk at NFL gambling sites. The San Francisco 49ers aim for a third win in a row to improve to 3-1 on the season. The San Francisco 49ers have split their last six games at home. Nick Mullens is completing 70.2% of his passes for 414 yards, one TD and one pick. Mullens and Jimmy Garoppolo combine for five TD passes and one pick this season.

Kendrick Bourne and Raheem Mostert have 274 receiving yards and one TD. Brandon Aiyuk has seven catches. The San Francisco 49ers are averaging 132.7 rushing yards per game. Robert Mostert has 148 yards and one touchdown. San Francisco is yielding 15.3 points and 304 yards per game. Fred Warner has 28 tackles. Kerry Hyder Jr. has two sacks. Jaquiski Tartt has pick.

San Francisco is 5-2 ATS in their last seven games. And 15-5 SU in their last 20 games. The total has gone over in seven of San Francisco’s last 10 games against Philadelphia. San Francisco is 8-3 SU in their last 11 games at home. 0-5 ATS in their last five games when playing at home against Philadelphia. And 5-1 SU in their last six games against an opponent in the National Football Conference. The total has gone over in five of San Francisco’s last seven games against an opponent in the National Football Conference East division. The total has gone under in five of San Francisco’s last seven games in October. San Francisco is 7-3 ATS in their last 10 games in week 4.

Philadelphia Eagles vs. San Francisco 49ers Betting Pick

The San Francisco 49ers are the most banged-up team in the league. That includes Garoppolo who remains questionable. However, how could anybody be keen on backing the Eagles in their current shape. Regardless of how many points they get. It’d be nice for the 49ers to get some important players back from injury. Even without them, though, take San Fran and the points.

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