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Notre Dame vs. Ohio State Buckeyes NCAAF Betting Odds & Picks

College Football Best Betting Games

Top sports betting sites favor Ohio State Buckeyes over Notre Dame in their 2022 NCAAF season opening game.

Notre Dame vs. Ohio State Buckeyes Odds by MyBookie.ag

TeamSP/RLTOTALML
Notre Dame+15 ( -110 )58 ( -110 )+475
Ohio State-15 ( -110 )58 ( -110 )-650
Bet Now on this Game

Betting Notre Dame

The Irish are road dogs at the best online sportsbooks. The Notre Dame Fighting Irish will represent the University of Notre Dame in the 2022 NCAA Division I FBS football season. The Fighting Irish will play their home games at Notre Dame Stadium in South Bend, Indiana. They will compete as an independent. The school will be led by first-year head coach Marcus Freeman.

On December 2, 2021, after the departure of Brian Kelly for LSU, defensive coordinator Marcus Freeman was promoted to the head coach position. The following coaches also left Notre Dame. Wide receivers coach Del Alexander. Linebackers coach Jeff Quinn. Special teams coach Brian Polian left to LSU.

DL coach and recruiting coordinator Mike Elston left for Michigan. Running backs coach and run game coordinator Lance Taylor left to become OC at Louisville. Tight ends coach John McNulty left to become offensive coordinator at Boston College.

New coaches are Harry Hiestand Rehired (Offensive Line). Gerad Parker (Tight Ends). Al Washington (Defensive Line). Al Golden Hired (Linebackers and as Defensive Coordinator). Chansi Stuckey (Wide Receivers). Brian Mason (Special Teams). Deland McCullough (Running Backs).

Safety Brandon Joseph transferred in from Northwestern. Kicker Blake Gruppe transferred in from Arkansas State. Jon Sot transferred in from Harvard. Quarterback Brendan Clark transferred to Old Dominion. Wide receiver Lawrence Keys III transferred to Tulane.

Tight end George Takacs transferred to Boston College. Linebacker Quinn Carroll transferred to Minnesota. LB Shayne Simon transferred to Pittsburgh. Linebacker Paul Moala entered the transfer portal.

Notre Dame Stats

According to top sports betting sites, Notre Dame is 7-1 ATS in their last eight games. Notre Dame is 7-1 SU in their last eight games. Fighting Irish is 9-0 SU in their last nine games on the road.

Notre Dame is 5-1 SU in their last six games against an opponent in the Big Ten conference. The total has gone OVER in four of Notre Dame’s last five games played in September. Notre Dame is 9-2 ATS in their last 11 games played on a Saturday. Notre Dame is 6-1 ATS in their last seven games played on a Saturday when playing on the road.

Betting Ohio State Buckeyes

The Buckeyes football will represent Ohio State University in the 2022 NCAA Division I FBS football season. They will be led by fourth-year head coach Ryan Day. They will play their home games at Ohio Stadium in Columbus, Ohio.

This will be the Buckeyes’ 133rd season overall. And their 110th as a member of the Big Ten Conference. The Buckeyes hope to avenge their first rivalry defeat to Michigan after an eight-year winning streak.

The Buckeyes finished last season 11–2 (8–1 in conference play). They finished second in the East Division. They missed the Big Ten Championship for the first time since 2016 after they lost to Michigan for the first time since 2011. The Buckeyes earned a bid to the Rose Bowl. They defeated Utah 48–45.

According to top sports betting sites, Ohio State is 2-4 ATS in their last six games. The total has gone OVER in 13 of Ohio State’s last 19 games. Ohio State is 10-1 SU in their last 11 games. Buckeyes are 6-0 SU in their last six games at home.

Buckeyes Stats

Ohio State is 7-0 SU in their last seven games against an opponent in the Independents. The total has gone OVER in five of Ohio State’s last five games played in week 1. The total has gone OVER in six of Ohio State’s last nine games played on a Saturday. Ohio State is 4-1 ATS in their last five games played on a Saturday when playing at home.

Ohio State ranks No. 2 in the football preseason USA TODAY AFCA Coaches Poll. The poll was released on Monday. They are second only to top-ranked Alabama. Alabama received 54 of the 66 possible first-place votes.

The Buckeyes earned five first-place votes. The defending College Football Playoff champions Georgia Bulldogs got six first-place votes. The Bulldogs are No. 3. Texas is ranked 19th and also received one first-place vote.

The high preseason ranking for Ohio ST. comes as they are stacked on offense with several prominent returners, including star WB C.J. Stroud and receiver Jaxon Smith-Njigba.

Notre Dame vs. Ohio State Buckeyes NCAAF Pick

Ohio State will Win, Notre Dame will Cover, and the Total will go Over.