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There are a few considerable point spreads when we look at NFL gambling sites Week 6 betting odds. Aaron Rodgers and Green Bay are -7.5 faves over Zach Wilson and the NY Jets. Another one-sided line is Matthew Stafford and the LA Rams as -10.5 home chalk over the Panthers.

That line is not too much of a surprise if we consider that Carolina fired head coach Matt Rhule this week and Steve Wilks was appointed as the interim head coach. The line, though, would have been sizable regardless.

Tom Brady will be back in Pittsburgh, where his Bucs are -8.5 road faves over the Steelers. There are some thin point spreads in there, too. The Bengals (-2) face the Holy Ones in New Orleans. The Colts are also (-2) at home versus the Jaguars.

Commanders vs. Bears Odds by MyBookie.ag

Team SP/RL TOTAL ML
Commanders PK ( -110) 38 ( -110 ) -110
Bears PK ( -110) 38 ( -110 ) -110
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Bettors at the best online sportsbooks do not expect a lot of excitement from this torpid match-up that seems rather unworthy of a TNF prime time slot. The Bears still hold on as one-point home faves, but there has occurred a big downward swing with the total. After they opened as high as 40 the Over/Under did drop to 38.5 on Monday. That trend went on on Tuesday with most sportsbooks cutting the number to 37.5.

It is hard to gauge what Washington’s identity is at this point, other than as a pass-happy (well, not so much happy but you get the idea). The Commanders posted just 12 carries on Sunday and Wentz passed 38 times. That pushed the team’s pass play rate to 66.7%.

49ers vs. Falcons Odds

Team SP/RL TOTAL ML
49ers -5½ ( -110 ) 44½ ( -110 ) -245
Falcons +5½ ( -110 ) 44½ ( -110 ) +195
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The 5-0 ATS Atlanta Falcons did open as low as +5.5 for this clash with the Niners. Early action at NFL gambling sites is on San Francisco.

Patriots vs. Browns Odds

Team SP/RL TOTAL ML
Patriots +2½ ( -110 ) 43½ ( -110 ) +125
Browns
-2½ ( -110 )
43½ ( -110 ) -145
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In spite of a tough home loss to the Bolts on Sunday and the Patriots running through the Lions, some sportsbooks are as high as Cleveland -3.

Jets vs. Packers Odds by MyBookie.ag

Team SP/RL TOTAL ML
Jets +7 ( -105 ) 45 ( -110 ) +270
Packers -7 ( -115 ) 45 ( -110 ) -340
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Jaguars vs. Colts Odds

Team SP/RL TOTAL ML
Jaguars +1½ ( -110 ) 42 ( -110 ) +110
Colts -1½ ( -110 ) 42 ( -110 ) -130
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The condition of Indianapolis running back Jonathan Taylor will have an effect on this line as the week unfolds. Indy has enjoyed a mini bye since they squeaked out a gross win on last Thursday and they opened as 1.5-point home chalk to the Jags in Week 6. The Jags have lost back-to-back games and they haven’t looked anything like the team went on to shut out the Colts in Week 3.

Vikings vs. Dolphins Odds by MyBookie.ag

Team SP/RL TOTAL ML
Vikings -3½ ( -110 ) 45½ ( -110 ) -185
Dolphins +3½ ( -110 ) 45½ ( -110 ) +155
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There is a lot of uncertainty regarding Miami’s QB situation. Expect a lot of movement this week as the latest news becomes available.

Bengals vs. Saints Odds

Team SP/RL TOTAL ML
Bengals -2 ( -110 ) 43 ( -110 ) -130
Saints +2 ( -110 ) 43 ( -110 ) +110
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The total went down slightly and it sits now at 43.5 at most NFL gambling sites.

Ravens vs. Giants Odds

Team SP/RL TOTAL ML
Ravens -5½ ( -110 ) 45 ( -110 ) -250
Giants
+5½ ( -110 ) 
45 ( -110 ) +200
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The upstart Giants did open as 5-point home dogs as they come off a shocking 27-22 upset over the Packers in London.

Buccaneers vs. Steelers Odds by MyBookie.ag

Team SP/RL TOTAL ML
Buccaneers -8 ( -110 ) 44 ( -110 ) -400
Steelers +8 ( -110 ) 44 ( -110 ) +310
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The Steelers return home and they opened as 7.5-point underdogs as they host Tampa Bay in Week 6.

Panthers vs. Rams Odds

Team SP/RL TOTAL ML
Panthers +10½ ( -110 ) 41 ( -110 ) +375
Rams -10½ ( -110 ) 41 ( -110 ) -500
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Baker Mayfield suffered a high-ankle sprain and will be sidelined for Sunday’s game in LA against the Rams. Some might think this is good for the Panthers, but sportsbooks did adjust the spread to Rams -11 and also decreased the total from 41.5 to 40.5.

Cardinals vs. Seahawks Odds by MyBookie.ag

Team SP/RL TOTAL ML
Cardinals -2½ ( -115 ) 50½ ( -110 ) -145
Seahawks +2½ ( -105 ) 50½ ( -110 ) +125
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Arizona did open as 2.5-point road chalk and that point spread is as low as -2. It’s the total, though, that is the most intriguing number.

Bills vs. Chiefs Odds

Team SP/RL TOTAL ML
Bills -2½ ( -120 ) 54 ( -110 ) -145
Chiefs +2½ ( EV ) 54 ( -110 ) +125
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The total did open at 54 points and if the past few games between these two teams are some indication, that number may fall short.

Cowboys vs. Eagles Odds by MyBookie.ag

Team SP/RL TOTAL ML
Cowboys +6 ( -110 ) 42 ( -110 ) +220
Eagles -6 ( -110 ) 42 ( -110 ) -270
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Philadelphia did open at -5.5 as they host the Cowboys in a crucial NFC East game and some sportsbooks went down to -5 with early action on Dallas.

Broncos vs. Chargers Odds

Team SP/RL TOTAL ML
Broncos +5 ( -110 ) 45½ ( -110 ) +190
Chargers -5 ( -110 ) 45½ ( -110 ) -235
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The Broncos have enjoyed a mini-bye after they lost an ugly game on Thursday. Russell Wilson is nursing a torn lat muscle.

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