Florida State vs. Louisville Odds and Predictions

Florida State Seminoles vs. Louisville Cardinals odds and Picks

The Florida State Seminoles are slight favorites on Saturday as they visit the Louisville Cardinals in a game that can be seen on ABC. The Seminoles come into this game ranked 2nd in the country while the Cardinals are ranked 10th. The Seminoles are considered national title contenders while the Cardinals could get into that discussion if they can get this win on Saturday. It should be a high scoring game with the total at top sportsbooks listed at 65.

NCAA Football Odds at Online Sportsbooks

Florida State Seminoles -2, total 65

Top 10 Matchup

You can make a case that this is the second most important game of the betting season in the ACC behind only Florida State vs. Clemson. The Seminoles have a potent offense led by running back Dalvin Cook while the Cardinals have the best offense in the country led by Heisman Trophy candidate Lamar Jackson. The Cardinals have dominated two outclassed opponents, Charlotte and Syracuse by a combined 132-42. Jackson has accounted for more than 1,000 total yards and he has 13 TDs.

Florida State head coach Jimbo Fisher said he expects a very difficult game against Jackson and Louisville. “Got a great team coming up in Louisville, very dynamic on both sides of the ball, playmakers, kicking game. I mean, extremely well coached.” Fisher said, “You go from A to Z. They’re as good as there is around, so they do a great job. Got to get better, get ready for the challenge and get ready to roll.”

The Seminoles will be without their best defensive player, defensive back Derwin James who hurt his knee last week. Louisville head coach said that James is “one of the best players in the country.”

Saturday’s game could easily turn into a shootout as the Seminoles will be relying on freshman quarterback Deondre Francois, who has completed 69 percent of his passes and running back Dalvin Cook. On the other side, the Cardinals will be looking to Jackson who has been the most exciting player in the country so far this season. Jackson has accounted for 13 touchdowns this season. He could have a great day against an FSU secondary that is without James.

Game Trends

According to TopBet Sportsbook the Seminoles are 4-1 ATS in their last 5 conference games. The Cardinals are 5-2 against the spread at the best betting websites in their last 7 home games. The Cardinals are 2-5 ATS in their last 7 conference games.

The Under is 5-0 in the Seminoles last 5 road games. The Under is 9-3 in the Seminoles last 12 conference games. The Over is 4-0 in the Cardinals last 4 conference games. The Under is 11-5-1 in the Cardinals last 17 games in September.

NCAA Football Picks

The line at the best online betting sites that offer the best online sportsbook bonus has moved toward Louisville. This is a tough game to call so I will avoid a side and just take the game over the total.