The best sportsbooks favor the 49ers over the Lions on September 12, 2021, 1:00 PM ET at Ford Field.
San Francisco 49ers vs. Detroit Lions NFL Odds by BetOnline.ag
| Team | SP/RL | TOTAL | ML | |
|---|---|---|---|---|
| 49ers | -7½ (-105) | 45½ (-110) | -355 |  |
| Lions | +7½ (-115) | 45½ (-110) | +285 | |
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Betting San Francisco 49ers
The Niners are road favorites per the best online sportsbooks. The 49ers ranked eighth at 7.6 yards per pass attempt last year; the Lions allowed 8.5 yards per passing play. The San Francisco offense was No. 8 with a 67.3% red-zone percentage; Detroit’s defense was 31st with a 72.3% opponent red-zone rate.
The 49ers average of 270.0 passing yards per game was 10th in the NFL. They will be facing a Lions pass defense that allowed 297.1 per game, ranking 30th. San Francisco averaged 5.7 yards per play, as opposed to the 6.3 per play Detroit surrendered.
Jimmy Garoppolo had 1,096 passing yards (137.0 yards per game) and a 67.1% completion percentage last season (94-of-140). He threw seven touchdowns and five picks. Raheem Mostert ran for 521 yards on 104 carries (52.1 yards per game). He scored two TDs. He averaged 15.6 receiving yards per game, and grabbed 16 passes for 156 yards and one TD.
JaMycal Hasty tallied 148 rushing yards on 39 carries (18.5 yards per game). He scored one rushing touchdown. Brandon Aiyuk caught 60 passes for 748 yards and scored five TDs. On 96 targets, he averaged 46.8 yards per game.
George Kittle added 48 grabs for 634 yards and two TDs. On 63 targets, he averaged 63.4 receiving yards per game. Deebo Samuel nabbed 33 passes on 44 targets for 391 yards and one TD. He averaged 30.1 receiving yards per game.
Samson Ebukam boasted 4.5 sacks, 5.0 TFL and 44 tackles. Fred Warner totaled 170 tackles, 6.0 TFL, 1.0 sack, and two interceptions. Jason Verrett intercepted two passes. He added 70 tackles, 2.0 TFL, and seven passes defended.
San Francisco Betting Trends
According to the best sportsbooks, San Francisco is 3-6 ATS in their last nine games. San Francisco is 1-4 SU in their last five games. 49ers are 10-1 SU in their last 11 games against Detroit. San Francisco is 12-5 SU in their last 17 games on the road.
49ers are 4-2 ATS in their last six games on the road against Detroit. San Francisco is 2-6 SU in their last eight games against an opponent in the National Football Conference. 49ers are 4-2 ATS in their last six games against an opponent in the NFC North division. The total has gone OVER in six of San Francisco’s last nine games played in September.
Betting Detroit Lions
The Lions are home dogs on the best sportsbooks’ oddsboards. The Lions’ offense had the No. 30 rushing attack in the league last season (93.7 yards per game). They will face the No. 7 defense in that category; the 49ers yielded 106.4 rushing yards per game.
Detroit was 24th with 4.1 yards per carry; San Francisco allowed 4.0 per rushing attempt. The Lions ranked 20th gaining 350.2 yards per game last; the 49ers ranked fifth in yards allowed. Detroit had a 41.1% third-down conversion; San Francisco surrendered third-down conversions on 35.5% of its opponents’ attempts.
Jared Goff had 3,952 passing yards (247.0 yards per game) last season. He went 370-for-552 (67% completion percentage). He threw 20 touchdowns and 13 picks. D’Andre Swift produced 521 rushing yards (32.6 yards per game).
He scored eight TDs. He had 46 catches for 357 yards (22.3 receiving yards per game) with two receiving TDs. Jamaal Williams rushed for 505 yards on 119 carries (31.6 ypg). He scored two rushing TDs. T.J. Hockenson had 67 catches for 723 yards (45.2 ypg) and six TDs.
San Francisco 49ers vs. Detroit Lions NFL Pick
49ers win, cover.
