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San Francisco 49ers (1-1) vs. Los Angeles Rams (0-2)

San Francisco 49ers vs. Los Angeles Rams September 22 2024 – Week 3 of the NFL is upon us, and one of the intriguing fixtures features the San Francisco 49ers’ clash with the Los Angeles Rams. The 49ers, hoping to improve their record from the current 1-1, are faced with a winless Rams team that has yet to win a game this season, sitting at 0-2. This game attracts more interest than just the rivalry factors since it could also serve as a major turning point for both teams this season. This is also one game that bettors and fans seem to be waiting for, making it one of the highlights in daily NFL previews.

San Francisco 49ers vs. Los Angeles Rams September 22 2024 Game Info

When: Sunday, September 22, 2024 at 4:25 PM ET 
Where: SoFi Stadium 
TV: FOX 
Stream: NFL Game Pass

San Francisco 49ers vs. Los Angeles Rams Betting Odds

Team Moneyline Spread Total
49ers -180 -4 (-120) 46.5 over (-120)
Rams +152 +4 (-120) 46.5 under (-120)

The betting odds suggest a tilt in favor of the 49ers, who are expected to cover the spread against a Rams team that has shown resilience in ATS standings despite their losses. The total over 46.5 reflects expectations of a high-scoring game, potentially influenced by recent games where both teams have tended to exceed point expectations.

Brock Purdy QB vs. Matthew Stafford QB

Brock Purdy, quarterback for the 49ers, comes into this game with good statistics in the early part of the season with a 72.3% completion rate and 550 passing yards after two games. He was sacked 8 times but somehow still managed to make important passes, thus keeping the 49ers in the game. Maybe Purdy’s movement would give San Francisco the good they require to penetrate the Rams’ backline.

Matthew Stafford of the Rams might have a passer rating of 88.3 against Purdy’s 96.3, but he is also a big threat. His mind and how he plays the game is important particularly when he has already been put on the ground 7 times and game-planned pressure is building up. He has to hit serious threats like Cooper Kupp, with 147 yards received this season, to breach the 49ers’ much-touted defense.

Purdy’s duel with Stafford is sure to be interesting. Both quarterbacks possess different strengths on the field, and their performance may very well control the rhythm and the end result of the game. Purdy playing off Stafford’s accuracy suggests that a battle of physicality and technical skills will stir every football lover’s interest.

49ers’ Offensive Attack

Jordan Mason and Jauan Jennings have been instrumental in San Francisco’s offensive strategy. Mason, with an impressive average of 5.1 yards per carry, provides a solid ground game option, making key first downs and maintaining drive momentum. Jennings, although not scoring yet, plays a crucial role in stretching the defense, allowing for midfield openings that Purdy can exploit.

Rams’ Response on the Ground and Through the Air

Conversely, the Rams have seen mixed results from their rushing and receiving corps. Kyren Williams, although only averaging 2.5 yards per carry, has found the end zone twice, showing he can be effective in short-yardage, high-stakes situations. Kupp remains Stafford’s primary target, blending speed with route precision to challenge the 49ers’ secondary.

San Francisco 49ers Betting Trends

San Francisco are 1-5 ATS in their last 6 games.

The total has gone OVER in 8 of San Francisco’s last 12 games.

San Francisco are 10-4 SU in their last 14 games.

49ers are 7-2 ATS in their last 9 games against LA Rams.

San Francisco are 9-2 SU in their last 11 games against LA Rams.

Los Angeles Rams Betting Trends

LA Rams are 7-3 ATS in their last 10 games.

The total has gone OVER in 7 of LA Rams’ last 10 games.

The total has gone OVER in 4 of LA Rams’ last 6 games against San Francisco.

LA Rams are 5-1 SU in their last 6 games at home.

LA Rams are 1-5 ATS in their last 6 games when playing at home against San Francisco.

San Francisco 49ers vs. Los Angeles Rams Betting Previews

Upon assessing the complete information and previous records, it can be said that 49ers may be the desirable option this time, especially given their strong metrics against the Rams. But, there is a chance of an upset by the Rams, thus making the over on points total an interesting bet. Looking at player yards in prop bets can also be of good value for those looking at options on trusted betting sites, because of the offensive skills both teams possess.

In the end, though, this game should be hard fought, but slightly in favor of the 49ers owing to their all-around offensive and solid defense. Expect a thrilling contest which would be ideal for the tactical punter.

Score Prediction: 49ers 27, Rams 24.  

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