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San Francisco 49ers (6-10) vs. Arizona Cardinals (7-9)

San Francisco 49ers vs. Arizona Cardinals January 5 2025 – The Arizona Cardinals, with a record of 7-9, will take on the San Francisco 49ers, with a record of 6-10. Surprisingly, both of these teams have had an underwhelming season, but their offensive and defensive struggles are set for a remedy in an exciting and tantalizing Week 18 matchup at State Farm Stadium. This match not only changes their rankings but gives both teams a chance to redeem themselves with the regular season ending.

San Francisco 49ers vs. Arizona Cardinals January 5 2025 Game Info

When: Sunday, January 5, 2025, at 4:25 PM ET
Where: State Farm Stadium
TV: FOX
Stream: NFL Game Pass

San Francisco 49ers vs. Arizona Cardinals Betting Odds

Team Moneyline Spread Total
49ers -110 -2.5 (-112) Over 46.5 (-110)
Cardinals -110 +2.5 (-110) Under 46.5 (-112)

The odds suggest this is a competitive matchup – the 49ers are marginally favored. The point spread reveals that the San Francisco team is tipped to win by just above a field goal. In view of both teams’ recent form, the spread bets and total points might be of value to bettors.

Brandon Allen QB vs. Kyler Murray QB

Brandon Allen, who has been imposing himself on the 49ers of late, has had a terribly challenging season, which reflects in his stats. He has a disappointing completion rate of 56.7%, a completion of only 199 yards, and a passer rating of 60.3 over three outings. Considering his headshot the game preparing him for this game, they are likely to concede that his accuracy and penchant for throwing interceptions will likely not work in his favour.

On the other end, Kyler Murray of the Cardinals has been more consistent and efficient throughout the said season. With a completion rate of 68.6% and a yard record of 3609 yards passing, Murray has a much better standard of performance. Murray’s passer rating of 91.1 further consolidates his capability to not only make plays but regroup and keep moving regardless of intense pressure and focus from the defensive team.

The presence and movements of Brandon Allen along with Kyler Murray do make for an interesting tussle as the experience and performance gap may be a deciding factor. It may just be the case that the Cardinals will side with Murray’s flashy would-be passing and sloppy play and experience especially considering Allen’s bad propensity for turnovers when under pressure, the focus may well be on how each quarterback takes control and outsmarts the other rather focuses on the strength of the defence.

49ers’ Ground and Air Attack

Isaac Guerendo and Jauan Jennings stood out in what was otherwise a poor showing for the team against Detroit. Jennings and Guerendo have promise which would be necessary against the Cardinals. Jennings is a top notch receiver and Guerendo provides consistent backfield rushing which will be crucial in penetrating the Cardinals’ defenses.

Cardinals’ Offensive Strategy

For the Cardinals, James Conner supplied his usual quality rushing stats and Marvin Harrison Jr. had some spectacular receiving plays, regardless of the losses to the Rams and Panthers. They would be useful in getting the first down so as to take advantages of the weaknesses in the 49ers defensive set up.

San Francisco 49ers Betting Trends

San Francisco are 1-7 ATS in their last 8 games.

The total has gone OVER in 4 of San Francisco’s last 6 games.

San Francisco are 1-6 SU in their last 7 games.

San Francisco are 4-1 ATS in their last 5 games against Arizona.

San Francisco are 4-1 SU in their last 5 games against Arizona.

Arizona Cardinals Betting Trends

Arizona are 7-3 ATS in their last 10 games.

Arizona are 1-5 SU in their last 6 games.

The total has gone OVER in 5 of Arizona’s last 6 games against San Francisco.

Arizona are 4-1 ATS in their last 5 games at home.

Arizona are 1-4 SU in their last 5 games when playing at home against San Francisco.

San Francisco 49ers vs. Arizona Cardinals Betting Previews

According to the stats and trends, it seems reasonable to endorse the Cardinals on the grounds of their ATS record and home court advantage. The point spread does not leave a wide margin, and with the kind of slump that the 49ers have had of late, it can be sensible to wager on the Cardinals to cover the spread. Furthermore, the previous meetings of these teams which were characterized by high scores would make it reasonable to suggest that the total score going OVER could also be a safer bet.

In accordance with the deployed analysis, Arizona Cardinals to cover circumstances and the total points to go OVER are reasonable options. Each one of the teams has got offensive powers that would enable the total score to go higher than expected by the odds.

 

Score Prediction: Cardinals 28, 49ers 24.  

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