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Cardinals vs. 49ers NFL Week 11 Betting Odds and Analysis

San Francisco 49ers NFL Betting Season odds, expert picks and analysis

US betting sites favor the San Francisco 49ers by 10.5-points over the Arizona Cardinals in their Week 11 NFL game on November 17 at 1:05 p.m. PT at Levi’s Stadium.

Arizona Cardinals vs. San Francisco 49ers Odds by MyBookie.ag

Cardinals+10½ (-115)45 (-110)+385
49ers-10½ (-105)45 (-110)-485
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Betting Arizona Cardinals

The Cards lost their third straight game, 27-30, to Tampa Bay in Week 10. On the other hand, according to the best online sportsbooks, and as 5.5-point road dogs, Arizona covered their second game in a row. Starting QB Kyler Murray went 27 of 44 for 324 yards with three TDs and one pick. Wide receiver Christian Kirk caught those three scoring passes, he had 138 yards on six receptions.

Murray added 38 rushing yards on three carries. The Cards gained 417 total yards; 342 passing. Those are above-average numbers for their 18th-ranking total offense and 16th-ranked passing offense. On the other hand, they were held to 75 yards rushing; well below their 116.0 yards per game average. Arizona allowed 457 total yards and 339 yards through the air. The Cards have the next-to-last total and passing defenses.

Per US betting sites, Arizona is 5-1 ATS in their last six games overall. And 5-2 ATS in their last seven playing NFC West teams. The over is 5-1 in the Cardinals’ last six games in November.
“[Murray and Kirk] are the first quarterback-receiver duo under the age of 23 to record a three-touchdown game since the Minnesota Vikings’ Fran Tarkenton connected with tight end Charley Ferguson on Nov. 11, 1962, for three scores.

“I think consistency at the quarterback position always helps,” Kingsbury said of Kirk. “You look at those great ones, they always have a guy in place for a long time where you build that rapport, you build that trust, and you’re their guy. I think there’s a lot of factors that play into it,”” Arizona Sports.com informs us.

Betting San Francisco 49ers

The Niners’ undefeated streak came to an end on Monday Night against Seattle. San Fran lost 24-27 as 6.5-point home favorites, according to US betting sites. Starting QB Jimmy Garoppolo went 24 of 46 for 248 yards with one TD and one pick. Jimmy G was sacked five times. Wide receiver Deebo Samuel had 112 yards on eight catches. Running back Tevin Coleman had 40 yards on nine carries.

Despite the tepid offensive effort, San Francisco remains in the top 10 total offenses. And in the top 5 scoring offenses. And in the top 3 rushing offenses. The Niners allowed 336 total yards of which 189 came through the air. That’s more than their league-leading passing defense and second-best total defense are used to yielding.

The 49ers are 5-13 ATS in their last 18 meetings with the NFC. And 2-7 ATS in their last nine games against the NFC West. The over is 5-1 in the 49ers’ last six encounters with the NFC West.

“The 49ers list of injured players is long. It may be so long that they can’t suit up 46 players Sunday against the Cardinals. 14 players were either out of practice or limited Thursday, including tight end George Kittle and wide receiver Emmanuel Sanders. They were both out of practice for the second consecutive day,” reports Niners Wire.

Arizona Cardinals vs. San Francisco NFL Week 11 Game Pick

Debuting kicker Chase McLaughlin missed a would-be game-winning field goal in overtime. However, even if he had converted it, San Fran still wouldn’t have covered the point spread. And it was more injuries than Chase’s inexperience that cost them their unbeaten streak. The 49ers will beat the Cards, but it will be closer than those 10.5 points.